Tuesday, February 19, 2008

The miracle of Vitamin C

The ghost of Pauling is back and this time he has cancer in his sights. What will the Pharmas make of this? The will probably mix it with their own concoctions and go on to 'show' how their molecule works better with ascorbate than rival X molecule.

Research backs theory that vitamin C shrinks tumours.

By Jeremy Laurance, Health Editor
Tuesday, 28 March 2006

New research suggesting that vitamin C can be effective in curing cancer will renew interest in the "alternative" treatment for the terminal disease.

Three cancer patients who were given large intravenous doses over a period of several months had their lives extended and their tumours shrunk, doctors reported yesterday.

A 49-year-old man diagnosed with terminal bladder cancer in 1996 was still alive and cancer-free nine years later, having declined chemotherapy and radiotherapy in favour of regular infusions of vitamin C.

A 66-year-old woman with an aggressive lymphoma who had a "dismal prognosis" in 1995 was similarly treated and is still alive 10 years later. A 51-year-old woman with kidney cancer that spread to her lungs diagnosed in 1995 had a normal chest X-ray two years later. The findings were confirmed by pathologists. Although they do not prove the vitamin cured the cancer they do increase the "clinical plausibility" of the idea, the researchers say.

Vitamin C therapy was first promoted by Linus Pauling, the Nobel prize winner, 30 years ago. Dr Pauling's claims sparked the continuing boom in sales of vitamin C, but attempts to confirm his findings failed and high-dose vitamin C became an "alternative" therapy.

The latest study, published in the Canadian Association's Medical Journal, could trigger renewed interest in Dr Pauling's claims. Studies show that vitamin C is toxic to some cancer cells but not to normal cells. The problem has been delivering a high enough dose.

The researchers say attempts to replicate Dr Pauling's work failed because they used oral doses of the drug which is rapidly excreted. However, injections achieve blood levels 25 times higher that persist for longer. At these very high doses, the blood level of vitamin C is high enough to selectively kill cancer cells.

Several clinical trials of vitamin C therapy are about to start, including one at McGill University, Montreal, the authors say.



Anonymous Felix said...

This is a three case case series from nearly 2 years ago-why post it now?
It got 13 citations (http://scholar.google.com/scholar?hl=en&lr=&cites=13285349058001451044&start=0&sa=N), but none for any further studies, as far as I could see.
I've heard nothing to suggest there's anything promising in Vitamin C for cancer at the mo-and I've got my ear to the ground at the moment, because I've ben engaged in some quack combat over at MLMB.
Anyway, you can get the paper here (http://www.cmaj.ca/cgi/content/full/174/7/937) if you haven't already, but don't hold your breath..


2:10 PM  
Blogger Kebz said...

Thanks Felix. The only reason I posted it was because it appeared in the Independent yesterday and also because it had recently figured in discussions on the ML as an antiviral agent. I fully realise these are just case studies and almost meaningless without blinded randomised trials. Thanks for the paper link. My thinking is that work such as this goes against the theory that Pharma are engaged in some giant conspiracy against simple or unpatentable molecules. Many on the MLMB have recently argued otherwise.

7:38 PM  
Blogger Philip said...

This is just another one of your moans about the Guantánomaly, cunningly disguised so people won't turn away in boredom and go off to give Rowan "the Ayatollah" Williams a good kicking. The references to cancer (turrsm by any other name) and aggressive lymphoma (Tony Blair ditto) are obvious enough, but your mention of blinded randomised trials really give the game away.

11:28 PM  
Blogger Kebz said...

Damn your infidel hide, you've given my game away! Have you anything to say before I lop your head off whilst simultaneously preaching hatred of your enlightened western values and blowing myself up for the hell of it?

7:19 AM  
Blogger Philip said...

Decapitation by Islamic internet fiend - what a career move! Support freedom and buy my books. Commemorate my martyrdom and buy my books. Mainstream media coverage - reviewed by Christopher Hitchens - my face on YouTube!

I think you may be on to something here. Would you consider becoming my literary agent?

9:09 PM  
Blogger Kebz said...

As long as I get 50% percentage of your virgins, you're on.

9:13 PM  

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